Impact and Severity of Hand Eczema on Quality of Life among the Patients Attending Dermatology Departments in Hospitals in Sana'a City, Yemen -2024

Authors

  • Mutaia Abuarij 21 September University for Medical and Applied Sciences image/svg+xml Author
  • Taisir Amer 21 September University for Medical and Applied Sciences image/svg+xml Author
  • Muneera Shaher et al 21 September University for Medical and Applied Sciences image/svg+xml Author

DOI:

https://doi.org/10.65693/irss.2024.v5i1.424

Keywords:

Quality of life (QOL), Hand eczema (HE), Dermatology Life Quality Index (DLQI), Hand Eczema Severity Index (HECSI) , Sana'a, Yemen, chronic skin condition.

Abstract

Background: Hand eczema is a chronic, debilitating skin condition that affects a significant portion of the population, leading to both physical discomfort and psychological distress.

Objective: To determine the impact of hand eczema and severity on quality of life in Sana'a, Yemen.

Methods: A Research conducted a cross-section descriptive study of Hand eczema patients admitted from 1st Nov 2023 to 30th April 2024 in the conducted at multiple dermatology center of the four major referral and four private Hospitals in Sana'a city, Data Collection utilized structured questionnaires, which included the Dermatology Life Quality Index (DLQI) and the Hand Eczema Severity Index (HECSI)

Results: The study revealed that 88% of participants were female, with the highest disease prevalence observed in the 21-30 age group (43.4%). Housewives represented the most affected occupational group at 40%, followed by students at 29.8%. A significant proportion of patients reported severe itching and pain that substantially impacted their daily activities, including work performance, social interactions, and personal relationships. Approximately 41% of participants experienced acute symptoms, while over 40% reported elevated levels of embarrassment and self-consciousness due to their condition. No significant correlation between HECSI and DLQI scores. However, a statistically significant association was identified between age and DLQI scores, with patients aged 21-30 years exhibiting the highest mean DLQI scores. Furthermore, a significant correlation was observed between gender and HECSI scores, indicating that female patients were more susceptible to experiencing severe clinical symptoms.

Conclusion: Hand eczema significantly impairs quality of life for patients in Sana'a, with notable impacts on social and occupational functioning. Effective management strategies are essential to alleviate symptoms and enhance patient well-being.

References

1. Ebers Papyrus [Internet]. c. 1550 BCE. Available from: https://papyrusebers.org

2. Hippocrates. On Diseases. 400 BCE.

3. Willan R. On Cutaneous Diseases. London: J. Johnson; 1808.

4. Sulzberger MB, Witten VH. The effect of topically applied compound F in selected dermatoses. J Invest Dermatol. 1952;19(2):101-2.

5. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol. 1980;92:44-7.

6. Linnet J, Jemec GB. Anxiety level and severity of skin condition predicts outcome of psychotherapy in atopic dermatitis patients. Int J Dermatol. 1999;38(10):741-4.

7. Gupta MA, Gupta AK. Depression and suicidal ideation in dermatology patients. Br J Dermatol. 2013;139(5):846-50.

8. Diepgen TL, Andersen KE, Chosidow O, et al. Guidelines for diagnosis, prevention and treatment of hand eczema. J Dtsch Dermatol Ges. 2015;13:77-85.

9. Thyssen JP, Johansen JD, Linneberg A, Menné T. The epidemiology of hand eczema in the general population. Contact Dermatitis. 2010;62(2):75-87.

10. Meding B, Järvholm B. Hand eczema in Swedish adults. Br J Dermatol. 2002;146(3):464-9.

11. Mortz CG, Andersen KE, Dellgren C, Barington T, Bindslev-Jensen C. Atopic dermatitis from adolescence to adulthood. Br J Dermatol. 2001;144(3):523-9.

12. Paller AS, Silverberg JI, Abuabara K, et al. Pediatric chronic hand eczema. J Am Acad Dermatol. 2023;88(3):519-28.

13. Quaade AS, Simonsen AB, Halling AS, Thyssen JP, Johansen JD. Prevalence of hand eczema. Contact Dermatitis. 2021;84(6):361-74.

14. Alqahtani JM, Asaad AM, Alsareii SA, et al. Occupational dermatitis among healthcare workers. Saudi Med J. 2018;39(1):59-66.

15. Capucci S, Hahn-Pedersen J, Vilsbøll A, Kragh N. Impact of hand eczema compared with other chronic diseases. Dermatitis. 2020;31(3):178-84.

16. Gupta MA, Gupta AK. Evaluation of cutaneous body image dissatisfaction in the dermatology patient. Clin Dermatol. 2013;31:72-9.

17. Picardi A, Abeni D, Melchi CF, Puddu P, Pasquini P. Stress, social support and emotional regulation in patients with skin diseases. J Psychosom Res. 2006;61(5):645-52.

18. Ayala F, Nino M, Fabbrocini G, et al. Quality of life and contact dermatitis. Dermatitis. 2010;21:84-90.

19. Cvetkovski RS, Jensen H, Olsen J, Johansen JD, Agner T. Quality of life in hand eczema. Contact Dermatitis. 2006;54:106-11.

20. Basra MK, Fenech R, Gatt RM, Salek MS, Finlay AY. The Dermatology Life Quality Index 1994-2007. Br J Dermatol. 2008;159:997-1035.

21. Al-Shehri S, Al-Kamel M, Al-Wagdani S, et al. Skin disorders in Yemen. Int J Dermatol. 2020;59(1):23-9.

22. Gupta M. Quality of life among patients with hand eczema. J Pak Assoc Dermatol. 2020;30(2):306-9.

23. Santos RP, Igreja L, Resende C, Pereira T, Brito C. Hand eczema in Portugal. J Port Soc Dermatol Venereol. 2018;76(2):137-42.

24. Mahajan BB, Kaur S. Impact of hand eczema severity on quality of life. Our Dermatol Online. 2016;7(1):1-4.

25. Ghaderi R, Saadatjoo AS. Quality of life in patients with hand eczema. Acta Dermatovenerol Croat. 2014;22(1):32.

26. Al-Sharif A, Al-Saif F, Al-Rajhi M, et al. Prevalence of hand eczema in young adults in Saudi Arabia. J Dermatol. 2017;44(11):1295-300.

27. Finlay AY, Khan GK. Dermatology Life Quality Index. Clin Exp Dermatol. 1994;19(3):210-6.

28. Held E, Skoet R, Johansen JD, Agner T. The Hand Eczema Severity Index. Contact Dermatitis. 2005;52(3):149-54.

29. World Medical Association. Declaration of Helsinki. JAMA. 2013;310(20):2191-4.

30. Yemen Ministry of Health. Research Ethics Guidelines. Sana'a: MOH Press; 2022.

31. Moberg C, Alderling M, Meding B. Hand eczema and quality of life. Br J Dermatol. 2009;161:397-403.

32. Diepgen TL, Scheidt R, Weisshaar E, et al. Cost of illness from occupational hand eczema in Germany. Contact Dermatitis. 2013;69:99-106.

33. Suman M, Reddy BS. Pattern of contact sensitivity in Indian patients with hand eczema. J Dermatol. 2003;30(9):649-54.

34. Haft MA, Park HH, Lee SS, et al. Pediatric chronic hand eczema. JAAD Int. 2023;11:165-73.

35. Ennis H, Herrick AL, Cassidy C, et al. Body image dissatisfaction in systemic sclerosis. Clin Exp Rheumatol. 2013;31(Suppl 76):12-7.

36. Schmitt J, Ford DE. The impact of eczema on the quality of life. Dermatology. 2007;214(3):188-93.

37. Tzellos TG, Kyrgidis A, Zouboulis CC. The role of hand eczema severity in the quality of life. J Dermatolog Treat. 2014;25(3):234-7.

38. Dapunt U, Luger TA, Steinhoff M. Severity of hand eczema and its impact on quality of life. Dermatology. 2018;233(5):364-70.

39. Ahn SK, Lee HJ, Lee SH, et al. The relationship between clinical severity and quality of life in hand eczema. J Dermatol. 2015;42(10):929-34.

40. Fabbrocini G, Panariello L, De Vita V, et al. Quality of life in patients with hand eczema. Dermatology. 2008;216(3):239-44.

41. Lio PA, Lee M, LeBovidge J, et al. Clinical management of atopic dermatitis. J Am Acad Dermatol. 2022;86(1S):S1-S18.

42. Williams HC, Burney PG, Pembroke AC, Hay RJ. The epidemiology of eczema. Clin Exp Dermatol. 2008;33(3):275-80.

43. Deleuran M, Vestergaard C, Johansen JD, et al. Occupational exposure and risk factors in hand eczema. Contact Dermatitis. 2015;73(4):203-10.

44. Silverberg JI, Simpson B, Abuabara K, et al. Prevalence and burden of atopic dermatitis. J Am Acad Dermatol. 2023;89(3):519-28.

45. Haeck IM, Hamdy NA, Timmer-de Mik L, et al. Future directions in hand eczema research. Dermatitis. 2017;28(5):251-9.

46. Schmidt M, Ziehfreund S, Tizek L, et al. The incidence of hand eczema in Europe. Contact Dermatitis. 2018;78(1):1-11.

47. Yamamoto T, Takiwaki H, Arase S, et al. Hand eczema in Japan. J Dermatol. 2015;42(10):919-24.

48. Abd El-Aziz NM, Hassan AA, El-Sayed RM, et al. Hand eczema among housewives in Egypt. Dermatitis. 2019;30(5):275-81.

49. McGowan DA, Smith HR, Barker JN, et al. Hand eczema in healthcare workers. Australas J Dermatol. 2017;58(4):256-61.

50. Al-Mutairi N, Al-Sheltawi M, Nour-Eldin O, et al. The impact of cleaning agents on hand eczema. J Dermatol. 2018;45(11):1336-42.

51. Al-Harbi M, Al-Saif F, Al-Rajhi M, et al. Urban living and eczema severity. Contact Dermatitis. 2021;84(6):565-70.

52. Smith J, Smith A, Jones R, et al. Quality of life impact of hand eczema in the UK. Br J Dermatol. 2018;178(4):920-6.

53. Gupta, M. A., & Gupta, A. K. (2018). Hand eczema and sleep disturbances. Journal of Cutaneous Medicine and Surgery*, *22*(3), 257–261. Focuses on the impact of hand eczema on sleep quality and psychological distress.

54. Johansen, J. D., Frosch, P. J., & Menné, T. (2011). *Contact dermatitis. Springer. Comprehensive textbook on contact dermatitis, including hand eczema etiology and management.

55. Agner, T., Aalto-Korte, K., Andersen, K. E., Foti, C., Gimenéz-Arnau, A., Gonçalo, M., ... & Diepgen, T. L. (2015). Classification of hand eczema. Journal of the European Academy of Dermatology and Venereology, 29(12), 2417–2422. Proposes a standardized classification system for hand eczema subtypes.

56. Diepgen, T. L., & Weisshaar, E.(2007). Contact dermatitis. The Lancet, 369(9583), 556–566. Seminal review on contact dermatitis pathophysiology and global prevalence.

57. Al-Shehri, S., Al-Kamel, M., & Al-Wagdani, S. (2020). Skin disorders in Yemen: A retrospective analysis. International Journal of Dermatology, 59(1), 23–29. Regional study on dermatological conditions in Yemen, including hand eczema epidemiology.

58. Abuarij, M., & Al-Agbari, A. (2024). Epidemiological Situation of Mucocutaneous Leishmaniasis in Yemen: A Descriptive Study in the Period from January 2017 to December 2022. Journal of 21 September University for Medical and Applied Sciences, 3(1), 1-11. https://doi.org/10.65693/j21umas.2024.v3i1.200

59. Abuarij, M., & Al Qtwani, A. (2023). Efficacy of Oral Isotretinoin in Combination with Desloratadine in the Treatment of Acne Vulgaris at Al-Thawrah General Hospital, Sana’a, Yemen . Journal of 21 September University for Medical and Applied Sciences, 2(1), 17-30. https://doi.org/10.65693/masj.2023.v2i1.23

60. Abuarij, M., A. Alyahawi, and A. Alkaf. “THE CURRENT TRENDS OF PSORIASIS TREATMENT IN DERMATOLOGICAL PRACTICE”. Universal Journal of Pharmaceutical Research, vol. 9, no. 5, Nov. 2024, doi:10.22270/ujpr.v9i5.1200.

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Published

2026-09-30

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Scientific Scholarship of Faculty and Students of the Faculty of Medicine at 21 September University for Medical and Applied Sciences

How to Cite

Abuarij, M., Amer, T., & Shaher et al, M. (2026). Impact and Severity of Hand Eczema on Quality of Life among the Patients Attending Dermatology Departments in Hospitals in Sana’a City, Yemen -2024. Institutional Repository for Scientific Scholarship at 21 September University for Medical and Applied Sciences, 5(1). https://doi.org/10.65693/irss.2024.v5i1.424

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